LifeCells® tablets Comprehensive Antioxidants  First time in India, Antioxidant of the Century, Comprehensive Formula.

Are antioxidant supplements good, bad, or completely unnecessary?

What are antioxidants?
Antioxidants can fight against free radical damage, which helps us to stay healthy and live longer. As a result, many people are taking antioxidant supplements as part of their diet. However, despite their many health benefits, scientific studies have proven that artificial supplements aren’t necessarily the answer. So, below we will look at what’s good and bad about antioxidant supplements and whether they’re needed.

Free radicals and the process of oxidation in the body.

When the oxygen that you breathe in through your lungs is metabolized into your blood, it creates unstable molecules known as ‘free radicals’, these are destructive molecules which can cause damage to your DNA and cell membranes. While the body does need some free radicals to function, if there are too many built up in a person’s system then the damage can become irreparable and may lead to diseases such as cancer, cardiovascular disease, liver disease, and many others.
Antioxidants are naturally found in a number of foods and these cells can, to some extent, prevent free radicals from damaging your cells by neutralizing them. These antioxidants can be found in vitamins A, C and E, in the minerals selenium, zinc and copper, and can also be found in phytochemicals from plants, fruits and vegetables.

What’s good about antioxidant supplements?
They help fight against aging, cancer and chronic diseases.

Antioxidants minimize damage to your cells from oxidants (aka free radicals), and can help fight against aging, cancer, and chronic diseases like cardiovascular disease. This has been proven by a study published in January 2008, which showed that taking antioxidant supplements like selenium could have ant-carcinogenic effects.

They remain safe from damaging free radicals?

Antioxidants also don’t run the risk of getting damaged or turning into free radicals themselves when reacting with free radicals. 

What’s bad about antioxidant supplements?
They prevent your body from making its own antioxidants
Your body makes its own natural antioxidants, which can actually be prevented if you take antioxidant supplements. Although the supplements provide you with antioxidants, they can’t balance the loss of your own antioxidants which are produced naturally rather than artificially.

They can’t prevent or cure all your ailments.

Taking vitamin C won’t prevent you from catching a cold and taking vitamin E won’t prevent you from aging or getting heart disease. Vitamin supplements also can’t prevent you from getting mental illnesses like schizophrenia or bipolar disorder. While it has been proven that antioxidants can decrease the likelihood of you contracting one of these diseases, it by no means guarantees you won’t develop them anyway.

They act as pro-oxidants when taken at high concentrations.

A research study published on 9 April 1998 found that vitamin C supplements can act as a pro-oxidant when taken at high concentrations. This is because vitamin C reacts not only with free radicals but also with other molecules in the body. One of these reactions is the Fenton Reaction, which was described in a study published in June 1999. It produces extra free radicals, so the antioxidant supplements become ineffective at stopping the production of free radicals. Artificially produced antioxidants are particularly ineffective against these free radicals as compared to natural antioxidants produced by the body.

They also harm your body when taken in high doses.

If you don’t have a vitamin deficiency and you take high doses of vitamin A, D, E or K (fat-soluble antioxidants that can be stored in the body) for a long time, they could become toxic and harm your body. Water-soluble antioxidants can also give you side effects if taken in large doses, e.g. vitamin B6 can cause nerve damage, whereas vitamin C can cause nausea, abdominal cramps, fatigue, headaches, diarrhea and kidney stones. High doses of vitamin C can also lead to dangerously high levels of iron, for example, as it interferes with the body’s ability to process or ‘metabolize’ other nutrients.

They increase your risk of developing cancer or do nothing at all.

The above-mentioned study published in January 2008 also showed that taking beta-carotene supplements can increase a smoker’s risk of getting cancer and dying from it, while vitamin E supplements had no effect.

They reduce the health-promoting effects of exercise.

Another research study published on 26 May 2009 found that taking antioxidant supplements could decrease the health-promoting effects of exercise (e.g. building muscle, improving your life expectancy, reducing your diabetes risk). Athletes and gym-goers who took antioxidant supplements to fight the extra free radicals produced by the body during exercise prevented their bodies from receiving the full health benefits of exercise.

They affect cancer treatments and medical tests.

A breast cancer study published on 15 July 2009 found that 70% of women who took vitamin supplements during their cancer treatments, experienced a reduced effectiveness in their (e.g. radiation therapy, chemotherapy) from working properly. The reason is because the supplements helped protect cancer cells by getting rid of the cancer-fighting free radicals produced by the treatments. Consuming large amounts of vitamin C can also interfere with medical tests, e.g. when taking a test for diabetes, it could give a false result.

They increase your risk of early death or, again, do nothing at all.

A review published on 14 March 2012, which included 78 randomized clinical trials that looked at 200,000 healthy people and 81,000 people who had different types of diseases, revealed that there was no evidence to prove the benefits of taking antioxidant supplements. Moreover, those who took beta-carotene and possibly vitamins A and E had an increased risk of early death.
More recent research, published on 10 July 2014, also showed that taking antioxidant supplements can shorten one’s life expectancy. Lung cancer patients who took supplements in addition to taking natural sources of antioxidants (e.g. food) ended up dying sooner instead of living longer. This is because when antioxidants are added to foods, healthy parts of whole foods go missing (e.g. fiber). This means that antioxidant supplements won’t be as successful in preventing diseases as a diet rich in natural antioxidants.

Are antioxidant supplements unnecessary?
Some people need supplements.

You should only take antioxidant supplements if recommended by your doctor or health practitioner, which is especially the case if you have an inadequate diet. If you do need them, take multivitamin supplements at the recommended dietary intake, instead of taking single vitamin supplements and in high doses.
People who can benefit from taking supplements include pregnant and breastfeeding women, those who consume lots of alcohol, drug users, those on long-term restrictive weight loss diets, the elderly, and those with malabsorption problems (e.g. diarrhea, pancreatitis, coeliac disease and cystic fibrosis).
For women planning to get pregnant, folic acid supplements can reduce the risk of their baby getting neural tube defects (e.g. spina bifida). For people on a vegan diet, particularly if they’re pregnant, they may benefit from taking vitamin B12 supplements.

Free radicals can be good for you.

Free radicals can be beneficial to you and your body. For example, when you exercise you produce extra free radicals that are essential to the health benefits that exercise brings, meaning that these extra free radicals trigger your cells to make your own antioxidants which give you the benefits of exercise. So, taking antioxidant supplements during exercise is unnecessary. Free radicals can also be helpful in an oxidative burst – this is when phagocytes (special immune cells) release free radicals to get rid of bacteria and viruses.  

Antioxidants can be taken from natural, healthier sources.

Antioxidants can be taken from a variety of natural foods and drinks, which is a healthier option. This includes: 

• Vitamin A from foods rich in beta-carotene (e.g. carrot, beetroot, sweet potato, spinach).
• Vitamin C from citrus fruits, berries, raw cabbage and broccoli.
• Vitamin E from wholegrains, nuts, fish oil, and green leafy veggies.
• Beta-carotene and its related carotenoids (e.g. lycopene, lutein) from fruits and veggies of a red, yellow, and orange colour.
• Selenium and manganese minerals from seafood, lean meat, nuts, and whole grains.
• Flavonoids from tea, coffee, and berries.
• Resveratrol from red wine and dark grapes.
• Phytoestrogens from peanuts and soybeans.

 

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Wonderful Product FolliCells Tablets are a dietary supplement designed for Hair growth , Support for Falling of Hair, Premature Greying of Hair, Brittle Nails, & Skin
 

• Introduction

Healthy looking hair is in general a sign of good health and good hair-care practices. Most healthy individuals have adequate nutrients in their diet; however, some people do not have access to good nutrition, others have medical illnesses that predispose them to nutritional deficiency which influence scalp / body hair.]
Nutrition is a complex subject - the effects of correct nutrition are indirect and often slow to appear. Hair in particular is slow to respond to any stimulus. Trials have indicated that correct nutrition is instrumental in healthy hair growth, and conversely many deficiencies correlate with hair loss. 
Hair nutrition is therefore a vital part of any treatment regime. A truly systematic and rigorous approach must be taken when formulating a nutritional supplement for hair due the many factors that affect the eventual efficacy of the treatment. 
Malnutrition, congenital heart disease, neuromuscular disease, chronic illnesses, malignancy, alcoholism, and advanced age can cause hair to change colour, be weakened, or lost. 
Genetics and health are factors in hair wellbeing. Proper nutrition is important. The living part of hair is under the scalp skin where its root is housed within its follicle. It derives its nutrients from blood.  Health concerns e.g. stress, trauma, medications, medical conditions, heavy metals, smoking etc. can affect the hair.
Hair is the fastest growing natural tissue in the human body: the average rate of growth is 1 cm per month. Optimal growth occurs from age 15 - 30 and reduces from age 40 - 50. Hair products (shampoos or vitamin supplements) have not been shown to noticeably change this rate. The cycles of growth of each follicle consist of creation followed by self-destruction. During each new cycle the follicle is built anew from raw materials.
The speed of hair growth varies based upon genetics, gender, age, hormones. It may be reduced by nutrient deficiency (i.e., anorexia, anemia, zinc deficiency) and hormonal fluctuations (i.e., menopause, polycystic ovaries, thyroid disease).
It is important to mention that many of the metabolic requirements of follicle cells (minerals and vitamins) must be satisfied for optimal hair growth (not always derived from fast foods and punishing work schedules). 
Nutritionists confirm that people with certain nutritional deficiencies tend to have dry, stringy and dull hair, and sometimes experience hair loss. Fortunately, the latter can be restored once the deficiency is addressed.
Crash diets cause temporary hair loss due to incumbent nutritional factors e.g. anorexia, bulimia and other medical conditions.
Diets should contain protein, fruits, vegetables, grains, and an appropriate amount of fat.  Deficiency will typically show in the hair.  A mild case of anemia can cause shedding of hair.  B group vitamins are significantly important for healthy hair, especially biotin. 
When the body is under threat it reprioritizes its processes - the vital organs will be attended first - hair follicles may not be considered a priority. While not all hair growth issues originate from malnutrition, it is a valuable symptom in diagnosis.
The essential omega-3 fatty acids, protein, vitamin B12, and iron, found in fish sources, prevent a dry scalp and dull hair color. Dark green vegetables contain high amounts of vitamins A and C, which help with production of sebum and provide a natural hair conditioner. Legumes provide protein to promote hair growth and also contain iron, zinc, and biotin. Biotin functions to activate certain enzymes that aid in metabolism of carbon dioxide as well as protein, fats, and carbohydrates. A deficiency in biotin intake can cause brittle hair and can lead to hair loss. In order to avoid a deficiency, individuals can find sources of biotin in cereal-grain products, liver, egg yolk, soy flour, and yeast. Nuts contain high sources of selenium and therefore are important for a healthy scalp. Alpha-linoleic acid and zinc are also found in some nuts and help condition the hair and prevent hair shedding that can be caused by a lack of zinc. Protein deficiencies or low-quality protein can produce weak and brittle hair, and can eventually result in loss of hair color. Low-fat dairy products are good sources of calcium, a key component for hair growth. A balanced diet is necessary for a healthy scalp and hair.
Healthy hair growth requires a complexity of nutrients and a ready supply of oxygen but comparatively few authoritive studies have trialled ingredients to maintain or promote hair growth.  However, a balanced, bioavailable formula to protect and maintain hair growth is vital. Dietary supplements marketed to thicken hair or make it grow faster may prove of nil value.
2. Vitamins
A good multivitamin can be a foundation of health and nutrition. Changes in skin and hair can provide clues to the presence of an underlying vitamin deficiency.
Hair ultimately reflects the overall condition of the body. In health problems or nutritional deficiencies hair may stop growing or become brittle. If a body is in good health, it is possible to maximize genetic growth cycle through taking the proper blend of amino acids and B-vitamins.
Certain vitamins, minerals and amino-acids are crucial to the metabolic pathways involved in keratin protein (hair) metabolism., leading to a potential loss of hair and substantial degradation of hair health. There is a rather adequate research basis to justify product effectiveness claims for a vitamin, mineral and amino-acid complex designed to supply the nutrients needed by healthy growing hair.
B5 (pantothenic acid) gives hair flexibility, strength and shine and helps prevent hair loss and greying. Vitamin B6helps prevent dandruff and can be found in cereals, egg yolk and liver. Vitamin B12 helps prevent the loss of hair and can be found in fish, eggs, chicken and milk.
It is also important to include B6, biotin, inositol and folic acid in the supplemental program. It has been found that certain minerals including magnesium, sulfur, silica and zinc are also very important toward maintaining healthy hair.
Vitamins B1, B2, Niacin & Pantothenic acid
Reduced levels of thiamin (vitamin B1), riboflavin (vitamin B2), niacin, and pantothenic acid can contribute to the undernourishment of hair-follicle cells. A dosage range of 25-50 mg daily is recommended.
Folic acid
A decrease in folic acid may contribute to decreased hair-follicle cell division and growth. Folic acid is also essential for the maintenance of healthy methionine levels in the body. Signs of folic-acid deficiency include anemia, apathy, fatigue, and graying hair. A therapeutic dose of 400-800 mcg daily is recommended.
Biotin
Biotin, part of the vitamin B complex, is another nutrient associated with hair loss. Biotin is required for a number of enzymatic reactions within the body, and is necessary for the proper metabolism of protein, fat, and carbohydrates. Over time, poor metabolism of nutrients can contribute to undernourished hair follicle cells. Although rare, a biotin deficiency results in skin rashes and hair loss. A study conducted at Harvard University suggests that biotin is one of the most important nutrients for preserving hair strength, texture, and function. 
People who are eating adequate amount of protein should not have a problem with biotin deficiency, though vegans may be at risk. Good food sources of biotin are eggs, liver and soy. 
It's not known if biotin supplements, which are marketed to help with male- and female-pattern baldness, can help with hair loss, and there are not any research indicating that the biotin in biotin hair products, such as shampoos, can be absorbed through the hair or scalp. The recommended dosage of d-biotin is 500-1000 mcg per day.
Vitamin C
One of vitamin C’s major functions is to help produce and maintain healthy collagen, the connective tissue type found within hair follicles. Vitamin C is also a strong antioxidant and protects both the cells found within follicles and cells in nearby blood vessels. A daily dose of 100-200 mg of vitamin C is recommended for hair and skin care. Vitamin C with bioflavonoids - one to two grams’ daily
Vitamin E
Vitamin E helps to maintain the integrity of cell membranes of hair follicles. The vitamin provides physical stability to cell membranes and acts as an antioxidant while promoting healthy skin and hair. A daily dose of vitamin E should be within the therapeutic range of 50–400 IU. Vitamin E and selenium work together to prevent attacks on cell membranes by free radicals by reducing peroxide concentration in the cell. Vitamin E - 400 to 800 IU daily

Beta-carotene

Beta-carotene is also important to hair growth. This is so because beta-carotene is converted to vitamin A as the body needs it, helps maintain normal growth and bone development, protective sheathing around nerve fibers, as well as promoting healthy skin, hair and nails. Dosage for Beta-carotene is 10,000 to 15,000 IU daily.



3. Antioxidants
Vitamins A, C and E are antioxidants that enhance skin cell turnover and collagen synthesis. When applied topically these vitamins protect against premature skin aging from the damaging effects of ultraviolet light and environmental pollutants.
Vitamin C helps reduce the damage caused by free radicals and UV exposure. Over time, free radicals can damage collagen and elastin, the fibers that support skin structure.
Vitamin E also helps reduce the skin effects of free radicals and UV exposure.
Selenium
Selenium is necessary for iodine metabolism. Case studies have indicated that selenium deficiency can lead to cancer, heart disease, and poor hair growth. Supplementation of 25-50 mcg of selenium per day is the recommended dosage.

4. Trace elements
Calcium - a fraction of the body’s calcium stimulates cell mediators that act on cell-membrane phospholipids in hair-follicle cells. Most Americans fail to meet the recommended daily intake for calcium. Patients have to be advised to take magnesium with supplemental calcium to maintain healthy calcium levels in the body. Without extra magnesium to balance it, large doses of calcium may be harmful. The recommended dosage is 100-200 mg of calcium per day.

Zinc is essential for DNA and RNA production, which, in turn, leads to normal follicle-cell division. Zinc is also responsible for helping to stabilize cell-membrane structures and assists in the breakdown and removal of superoxide radicals. Zinc intake is generally low. Topical applications of zinc have been shown to reduce the hair loss activity of 5-AR type II. The recommended dosage is 15 mg of zinc (in the form of zinc amino acid chelate) per day. 
Zinc deficiencies, and any associated hair health, may associate with low-calorie diets, especially young women. Zinc is found in meat, eggs and seafood.

Iron deficiency causes microcytic and hypochromic anemia. Moreover, most other organs including the skin and pilo sebaceous follicles are affected.
Iodine - Suboptimal thyroid functioning can lead to abnormal hair growth. Because iodine supports proper thyroid functioning, 112-225 mcg of iodine (in the form of kelp) per day is the recommended dosage.
5. Amino acids

L-Methionine, one of four sulfur-containing amino acids, supports hair strength by providing adequate amounts of sulfur to hair cells. Sulfur is required for healthy connective tissue formation. Hair requires sulfur for normal growth and appearance.
L-Cysteine - supports hair strength by the provision of Sulphur.  Skin, nails and hair are high in L-Cysteine. There is evidence that deficiency may be a factor in hair loss. Supplementing the diet accordingly may be helpful.
L-Lysine - It is interesting to note that male pattern baldness is less common in Asians than Americans. Is this in part due to the Asian diet being rich in L-Lysine -an enzyme inhibiting amino acid in vegetables and herbs affecting 5-alpha-reductase in some way.
6. Polyunsaturated fatty acids (PUFAs) - play an important role in cell structure, barrier function, lipid synthesis, inflammation and immunity. PUFAs help reduce dry, scaly skin. Most popular sources are walnuts, fish oil, flaxseed oil etc.
People on low-fat and non-fat diets are at risk for nutrition-related hair loss because hair needs essential fatty acids. Essential fatty acid deficiency causes a drying-up of the scalp and skin. These are vital nutrients that support follicular health. When the follicle is not healthy, hair loss or thinning occurs.
7. Aging effects there is no solution for this. Even with outstanding nutrition, genetic blueprint is eventually going to take control and hair may change in colour, structure and density. 
Control of biological aging may be influenced by superfoods e.g. super green mixes, chlorella, spirulina, micro-algae extracts such as astaxanthin, broccoli sprouts fresh vegetables blueberries, raspberries, strawberries, blackberries etc. also garlic, ginger and other culinary and medicinal herbs.
Water - is important in general bodily health and potentially good hair health. Water quenches thirst and aids food digestion.
8. Bioavailability
Many common vitamins and all amino acids exist as multiple isomers; however, it is rare that these are equally available to human metabolism. The chirality of amino acids is well established, as is the dramatic difference between left and right enantiomers in the human body. On the whole, humans can only metabolize left or L enantiomers, such as L-Cysteine. R-Cysteine is not taken up or commonly metabolized, therefore commonly used racemic mixtures of the two forms are only half comprised of useful amino acids.
Vitamins, such as vitamin B6 also have several forms, pyridoxine is the form of vitamin B6 most commonly used in nutritional supplements, however it is not the bio-active form. Instead it must be phosphorylated to become pyridoxal-5-phosphate, which is active as an enzyme cofactor for many reactions, and is important for uptake of other nutrients as well. The phosphorylation reaction to activate pyridoxine takes energy and a certain set of conditions, and therefore not all the pyridoxine taken in a supplement is used. A more efficient alternative is to use pyridoxal-5-phosphate in the supplement, so the bio-active form is immediately available, requiring no energy, and minimal wastage. 
Bioavailability is not just controlled by isomeric forms. Nutrient uptake is complex, and there are many surprising instances where one nutrient is dramatically affected – either negatively or positively, by a completely different nutrient in the formula.
9. Circulation
A final and often overlooked factor is the circulation of oxygen and nutrients to the hair. Even a perfectly balanced supplement would be ineffective without adequate blood flow to the hair. Hair loss may conceivably be caused or exacerbated by a deficient blood supply,. therefore, it may be beneficial to increase the circulation. This can be achieved through topical treatments that stimulate nitric oxide production or angiogenesis.
The stimulatory effects of caffeine and taurine on nutrient uptake and metabolism may also be beneficial. An added consideration is the possible effect of caffeine upon dihydrotestosterone and hair loss. Caffeine has been shown by several studies to reduce hair loss caused by dihydrotestosterone, the in vivo studies were successful topically, but the effects of oral caffeine have not been tested at this time. Taurine has also been shown by in vitro testing to protect the hair from TGFβ-1 induced apoptosis.
In spite of the paucity of clinical data in the area, it is possible through careful formulation to develop a potent, bioavailable, and balanced formula with combinations of ingredients that are likely to have good clinical outcomes. This is particularly true if supplements are used to support wider treatment regimens – even surgery.



What is oxidative damage?

Oxidation is the process whereby a molecule loses an electron and is cleaved into its substituent atoms or groups. Some of these species are left having an unpaired electron in their outer shell, which leaves them in a highly unstable and reactive state, as they are driven to complete their outer shells via pairing all electrons. These are called free radicals or reactive oxygen species (ROS).

In order to complete its outer shell of electrons, the free radical will attack adjacent molecules and abstract an electron from them, generating a new radical which is also unstable and seeks to “steal” an electron from its neighbors. This initiates a chain reaction, which is the basis of many polymerization reactions, but which can also be very destructive to living cells and systems. These free radicals can attack cell lipid layers, DNA, proteins, and many other essential structures, disrupting key biological processes and resulting in aging, decreased function, and pathological processes such as cancer.
Hair is not comprised of living cells, but its keratin-based structures are still susceptible to oxidative damage from a wide variety of sources. This damage leads to split ends, broken hairs, rough cuticles, frizz, tangling, lack of luster, diminished curl retention, and loss of color (natural or artificial). Identification of the many sources of free radical exposure can help a curly to reduce their overall risk of accumulating this type of structural degradation.

Exposure to ultraviolet radiation is one frequent route for oxidative damage, where the sun’s rays penetrate the hair shaft and deplete the natural melanin resident in the cortex and also alter the protein structures of both the cuticle and cortex. Chemical processes, particularly bleaching and permanent dyeing are culprits in the depletion of natural melanin and creating substantial oxidative damage. Additionally, relaxers, perms, keratin treatments, and heat styling contribute to formation of free radicals, which attack both the lipids and the proteins in the cuticle structures. Exposure to ozone, pollutants, tobacco smoke, substances in our water, as well as radiation all add to the continual exposure to free radicals and their damaging processes. Damage is pervasive and cumulative, and damaged hair becomes more porous and even more vulnerable to oxidative damage. For this reason, prevention and minimization are critical to preserve the health and beauty of hair.

Common Antioxidants
Vitamin E (α-Tocopherol)
Beta Carotene
Vitamin C
Vitamin A 
Phytochemicals
Plant extracts (green tea, grape seed extract, lemongrass, oolong, kiwi)
Selenium
Trace minerals

How Do Antioxidants Work?

We know from advertisements and reports in the media, as well as from more academic sources, that antioxidants are the key to dealing with this constant attack from free radicals, but what exactly is their role in the process? Antioxidants mitigate and prevent damage to cells and structures from free radical and reactive oxygen species by putting the brakes on the chain reaction that destroys everything around it. The mechanism by which they achieve this varies, depending upon the antioxidant, but generally it is accomplished via an electron or hydrogen donor process. These molecules are called free radical scavengers.

One common antioxidant is Vitamin E (α-Tocopherol), which donates an electron to an unstable free radical, rendering it stable, but becoming oxidized itself. However, rather than becoming a participant in the free radical chain reaction, the oxidized version of α-tocopherol is then either excreted or regenerated via reduction (hydrogen donation) by Vitamin C (ascorbic acid).

Effects for Hair?

While it is well-established that antioxidants are highly efficacious both when taken internally and applied to the skin via cosmetic preparations, it is natural to speculate whether or not they have equal value when applied topically to the hair, which is not a living cellular structure. Fortunately, the evidence indicates that there is plenty of benefit to be derived from the inclusion of antioxidants as components in formulations for rinse-off products, leave-in conditioners, and styling agents.
Vitamins and vitamin precursors such as Vitamin E, Vitamin C, and beta carotene have been found to have protective effects against environmental free radical assaults on hair. In a manner similar to sunscreens, these materials form a sort of interactive molecular shield against the elements, at least temporarily. By preventing the destruction of melanin and synthetic dye molecules in residence in the cortex of the hair strand, free radical scavengers can be quite useful in improving color retention and maintaining the health and integrity of hair. Experiments have also generated data that demonstrates the efficacy of topically applied antioxidants in mitigation of damage from both coloring and heat processes.

Oil soluble vitamins such as α-tocopherols and beta-carotene and vitamin A and lipophilic plant extracts are the more common antioxidants found in hair care preparations. The reason for this is that due to exposure to air many reactive oxygen species are generated in the aqueous phase in the bottle of product, where water soluble vitamins such as ascorbic acid (Vitamin C) would be present. The ascorbic acid is then rapidly depleted via oxidation reactions with the free radicals, and is thus comparatively short-lived in its availability to perform its preferred function on the hair.
One method chemists have used to circumvent this problem has been esterification of the ascorbic acid, which converts it to a lipophilic substance and increases its duration of efficacy. However, this additive is more expensive and diminishes its potential to scavenge radicals in the aqueous phase when hair is wet, which is when it is needed.

Furthermore, it is the assertion of research chemists at Mibelle Biochemistry in Switzerland that the inclusion of both water soluble and oil soluble antioxidants provides the best range of protection. For this reason they have been developing methods to include more stable water soluble antioxidants and blends (such as grape seed extracts + α-tocopherols) that provide highly effective protection of the cuticle and cortex, even in rinse-off products. Another research team has taken the approach of encapsulating ascorbic acid in micelles comprised of a nonionic surfactant (Polysorbate 80) and mixed tocopherols. This nanoemulsion is supplied as a gel-like aqueous solution that is easily mixed into a formula. The Vitamin C remains protected and active for a greater duration due to being in the interior of the micelle.

Conclusion

Our hair is being constantly bombarded by reactive species of molecules that slowly tear apart the very complicated biopolymeric structure of each strand. Without adequate protection, especially for longer hair, the damage grows continually worse until it becomes very evident. Color fades quickly. The surface becomes rough and porous. Tangles, breakage, and frizz become the norm. Curly hair, which has a rougher surface than straight hair is even more susceptible to this type of degradation. Fortunately, it has been found that some botanical oils, vitamin E, vitamin C, and beta carotene do indeed provide some protection against these environmental sources of free radicals. They also provide emollient properties and other benefits to the hair, and thus seem to be good additions to products for curly hair. They are not substitutes for wearing a hat and treating your hair kindly though, so protect those tresses!

The best antioxidant foods for hair loss

The Best antioxidant foods for hair loss. read everything here.
The best antioxidant foods for hair loss play a protective and vital role in our general health, including naturally the health of our follicles.
These foods are supposed to slow down the oxidation which is caused by the free radicals.
These are very reactive, unstable atoms created in our body that can damage cells leading to different of diseases and also ageing.
The Free-radical theory of aging says that these highly reactive oxygen species damage the proteins, the DNA, and other structures like the cell membranes.
The reaction of free radicals within cells, and the subsequent damage is connected to many disorders and chronic diseases such as inflammatory conditions, cancer, arthritis, alzheimer’s, diabetes and atherosclerosis.
Antioxidants foods can slow down or stop these dangerous reactions in our body, halting the oxidation reaction.
Antioxidants supplements can be taken as supplements or just as tablets, and can give different benefits to our health.
Some of the best antioxidant foods for hair loss are found in various forms – vegetables, fruits, grain cereals, legumes, nuts, etc.
Hair fall natural remedies
These can be considered as a hair fall natural remedy, and the sources of these antioxidants include berries, apple skins, peppers, cider, vegetables such as tea leaves and spinach, whole grain cereals (maize, hops, barley, nuts (almonds, pistachios and pecans and beans.
Polyphenol antioxidants are characterized by the presence of several phenol functions that can help fight the saw palmetto side effects, and are found in different phytonutrient-bearing ailments.
These foods include most of the legumes, cantaloupe, cherries, cranberries, blackberries, grapes, plums, and raspberries.
Among the vegetables we have parsley, broccoli, cabbage, and onion.
They are all rich sources of polyphenol antioxidants, and even if we can not consider them a top hair loss treatment, such as the Endhairloss.eu Full Program they can help slow down the excessive thinning.
Vitamins A, C and E are strong antioxidants too, while the animal form of vitamin A is called retinol.
This is a yellow, fat-soluble vitamin found in animal foods such as whole milk, eggs, and liver.
Vitamin C is a potent antioxidant that can help in maintaining healthy hair.
Good sources of this vitamin are foods such as kiwi, citrus fruits, pineapple, tomatoes, green peppers, and dark green vegetables.
This antioxidant can help increase scalp circulation and this is crucial for hair growth.
Also vitamin E is important for blood circulation and oxygenation.
You get it from foods like leafy green vegetables, dried beans, soybeans, raw seeds ad nuts.
The best antioxidant foods for hair loss described in this article may help you solve your problem, but they are not a definitive solution to baldness, such as our natural program, which can fight naturally the hormone DHT, enemy of the hair follicles.

Antioxidants For Hair

Antioxidants help reduce hair loss and speed up hair growth, but which foods and supplements contain the most antioxidants for hair?
In this article you’ll discover my favorite 27+ foods, herbs, spices and supplements that are bursting with hair growing antioxidant power.
One thing that’s important to note however is that although many people are eating more foods that are rich in antioxidants, they might not be getting any benefit from them whatsoever.
If the antioxidant foods are poorly combined or enter a digestive tract that is ‘backed-up’ and already covered in mucus they won’t be much good at all. In fact they could even make the situation worse.
That’s why it’s so important when eating healthy food to consume them in the right combinations, and ideally you’ve undergone a 7 day detox which has thoroughly cleaned out your colon, so you can properly absorb all the goodness of the foods.
Reducing free radicals with antioxidants may be one effective and natural way to stop your hair thinning.
Often people are willing to spend plenty of money on the latest super-antioxidant food, like blueberries, but consuming them on a full stomach or with a poorly functioning digestive tract means they will just ferment in the stomach and become nutritionally useless.
If you haven’t read the post of detoxing to reverse hair loss you really need to check it out. Also if you’re interested in knowing more about food combining to prevent hair loss then check out our ‘Hair Re-Growth Course.’
Anyway let’s get into it!
It is well known that free radicals contribute to premature aging, and as such they can be considered one of the mechanisms through which hair loss can take place in menaka male pattern baldness. Especially when present in the scalp free radicals might not cause hair loss in the first place but they certainly speed it up.
Keep your eyes open for another blog post where you can learn about the special mixture which can be applied to the scalp to conquer free radicals, amongst other things and actively encourage fresh hair growth in the scalp. However if they’re being produced in abundance from within the body then you’re fighting a losing battle.
Free radicals are formed when a weak bond of a molecule is split leaving an unpaired electron. This molecule is then left in need of another electron so it can become stable, but it must steal this from another molecule.
The result is a chain reaction of molecular damage (which leaves the cells in our bodies damaged and unable to function efficiently.) The faster our cells need to be repaired, the faster we age.
Smoking, pollution, radiation and inorganic chemicals found in our food and water all increase the number of free radicals in our bodies. And this is where antioxidants come in. Antioxidants break the chain reaction of free radical damage by donating one of their own electrons.
When free radical damage occurs in the scalp then the result is often damage to the hair follicle where it exits the skin and this inevitably leads to hair falling out, and growing back less often.
Ok, so let’s get straight to the point. What can we do to stop free radical damage as much as possible considering the amount of pollution and inorganic chemicals that we come into contact with in our modern lives?
Basically we need to eat more antioxidant foods, in the right combinations and timings with a cleaned out colon and efficiently functioning digestive system.
These are the best ones you can buy, but remember to see the detox section to make the most of them, otherwise most of the ‘goodness’ will just be coming out the other end and into the toilet.


 

MelaCells®  Tablets
Skin Reborn for a Lighter Tighter & Glowing Skin with MelaCells®  Tablets

Glutathione Uses & Benefits
 

• Glutathione is a master anti-oxidant and helps fight the free radicals
• It is anti-ageing in nature
• It is a part of the natural UV defense system and thus, protects the body from harmful UV rays

When the exact and correct amount of Glutathione dosage is taken, it helps in reducing the dark melanin pigments, and convert them into lighter pigments, thus, making the skin fairer, brighter and more even-toned.
Apart from the use of Glutathione for skin whitening, the Glutathione injections or pills are also given to treat the symptoms of various health complications and neurodegenerative diseases such as irritable bowel, chronic fatigue, stroke, multiple sclerosis, tremor, radical damage, etc.
All in all, there are many Glutathione benefits. Having mentioned that one should not ignore the Glutathione warnings. There are certain Glutathione side effects as well if this natural antioxidant is taken in a wrong way, in incorrect quantity or without the prescription of a specialist.

Glutathione is a tripeptide that's made up of the following amino acids: cysteine, glycine and glutamic acid. It is able to maintain human's health and performance and resist disease by neutralizing free radicals and keeping other antioxidants, including Vitamin C and E, in their active form. It also helps the liver to process toxins, helps with DNA and protein synthesis, and regulates both the nitric oxide cycle and the metabolism of iron. Glutathione helps to whiten the skin. Melanin is the pigment that gives our skin its color, produced by the activation of the enzyme Tyrosinase. GSH binds to Tyrosinase and helps prevent the enzymatic pathways from producing melanin. It can also give people with minor skin imperfections an overall better look by reducing the appearance of red spots and any rough patches that may exist. Many women use Glutathione exclusively to get smoother, more touchable skin. It may also have a beneficial effect for those that have cystic acne, acne-prone skin or even the occasional breakout.
Glutathione is a major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintains exogenous antioxidants such as vitamins C and E in their active form. Glutathione inhibits the melanin synthesis in reaction by inhibiting tyrosinase enzyme; leads to decrease in pigmentation.
ALA has the ability to chelate metals and to scavenge free radicals. It helps slow down the process of aging by improving blood flow and enhancing immune function, as well as positively affecting several other factors involved in aging.
Vitamin C
Vitamin C keeps skin well-toned. Vitamin C is the one that protects the skin against aging and sagging. With age, more vitamin C is essential to maintain elasticity. Free radicals disrupt collagens and elastin fibers that prominently help in maintaining skin texture. This disruption of skin essential components like collagen cause aging problems like wrinkles formation and premature aging. Vitamin C protects skin texture from getting damage.
The antioxidant properties of Vitamin C (ascorbic acid) and its role in collagen synthesis make Vitamin C, a vital molecule for skin health. Vitamin C may also help prevent and treat ultraviolet (UV) – induced photodamage.
Vitamin C, 
have anti-oxidant powers because they help fight off the damage caused by chemicals and toxins from our daily life. Sun exposure, tobacco smoke, pollution, and even stress hormones from our own body, makes us age. Not only do antioxidants combat the free-radical damage that is responsible for the visible (and hidden) signs of aging, they also enhance the effectiveness of sunscreens in preventing sun damage. Indeed, during the day, the combination of antioxidants plus sun protection is a strong defense against many signs of aging, including wrinkles, dullness, and discoloration.
Grape Seed Extract
Grape seed extract contains oligomeric proanthocyanidins, or OPCs. OPCs are powerful antioxidants; grape seed extract benefits the skin's appearance by bonding with collagen, which is the building block of healthy skin, to maintain skin cell health in addition to the skin's elasticity.
● Grape seed extract is a mixture of tannin and procyanidins. Extracts of grape seed are a great reservoir of natural antioxidants such as vitamin E, and flavones.

● Upregulation of peripheral nitric oxide (NO), a Vaso-relaxant.

● Down regulation of inflammatory cytokines that have been conclusively implicated in AGA.

● Potent free radical scavenging. Grape seed extract is a powerful antioxidant much greater than vitamin C and E. it also inhibits a number of enzymes that degrade connective tissue such as elastase, collagenase and hyaluronidase.
Vitamin E
Vitamin E is an antioxidant that protects and repairs the skin. It neutralizes the oxidant effect of free radicals, which are molecules that damage collagen and cause skin dryness, fine lines and wrinkles.
It restores moisture to skin and slows the aging of the skin cells. It is rich in antioxidants that protect the skin from free radicals.Vitamin E is the most important antioxidant because it protects cell membranes and prevents damages to enzymes associated with them. Vitamin e being fat soluble, is the primary antioxidant against free radical damage to lipids, including those make cell membrane.
Alpha Lipoic Acid

Alpha lipoic acid (ALA) is one of the most powerful anti-aging, antioxidant, anti-inflammatories available. ALA is called "the universal antioxidant" because it is both fat- and water-soluble. This means that ALA is easily absorbed through the lipid layers of the skin and works equally well as a free-radical fighter in the cell plasma membrane and in the watery interiors of the cell. This powerful metabolic natural substance has many benefits for skin care, including energy production in skin cells; regeneration of vitamins C and E; inhibiting the activation of transcription factor NF-kB; reduction of cellular inflammation; stimulation of AP-1, which helps remodel collagen; and protection of the skin from free radical inflammation, including sun exposure. Further, it is 400 times stronger than vitamins E and C combined (both of which are renowned for their antioxidant properties).Alpha lipoic acid sometimes referred to as the "Universal Antioxidant" because it regenerates or recycles other antioxidants like vitamin C, vitamin E, coenzyme Q₁₀ and glutathione when they lose their ability to act as antioxidants. It also has the power to protect both cell membranes and the inside of cells against oxidative damage. Vitamin E is only effective at protecting cell membranes and other lipid-soluble structures from oxidative damage, and vitamin C only works well in a non-lipid environment. Alpha lipoic acid works well in both of these areas.
Gallic acid: a versatile antioxidant with promising therapeutic and industrial applications
Abstract
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the leading cause of several degenerative diseases such as cancer, atherosclerosis, cardiovascular diseases, ageing and inflammatory diseases. Polyphenols form an important class of naturally occurring antioxidants, having innumerable biological activities such as anticancer, antifungal, antibacterial, antiviral, antiulcer and anticholesterol, to name a few. Among various polyphenols, gallic acid (3,4,5-trihydroxybenzoic acid), a naturally occurring low molecular weight triphenolic compound, has emerged as a strong antioxidant and an efficient apoptosis inducing agent. Starting from the bioavailability and the biosynthetic pathway of gallic acid, this review includes various in vitro, in vivo and in silico studies providing the mode of action, radical scavenging activity, ability to inhibit lipid peroxidation, maintenance of endogenous defense systems and metal ion chelation by this triphenolic molecule, along with a comprehensive overview of factors responsible for its high antioxidant activity. Gallic acid derivatives have also been found in a number of phytomedicines with diverse biological and pharmacological activities, including radical scavenging, interfering with the cell signaling pathways and apoptosis of cancer cells. The diverse range of applications of this simple polyphenol is due to a fine amalgam between its antioxidant and prooxidant potential. The existing literature on this dual behavior of gallic acid and its derivatives is reviewed here. This is followed by an account of their potential clinical and industrial applications.
 

Free radical studies of ellagic acid, a natural phenolic antioxidant.

Abstract

Ellagic acid, a plant-derived polyphenol, inhibits gamma-radiation (hydroxyl radical) induced lipid peroxidation in rat liver microsomes in a dose- and concentration-dependent manner. Its antioxidant capacity has been estimated using the 1,1-diphenyl-2-picrylhydrazyl radical assay. To understand the actual mechanisms involved in antioxidant activity and the free radical scavenging ability,a nanosecond pulse radiolysis technique has been employed. The rate constants for the reactions of several reactive oxygen species and reactive nitrogen species such as hydroxyl, peroxyl, and nitrogen dioxide radicals have been found to be in the range of 10(6)-10(9) M(-1) s(-1). The ellagic acid radicals have been characterized by the absorption spectra and decay kinetics. Studies on the reactions of ellagic acid with the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) radical and the radicals of ellagic acid with ascorbate have been used to estimate its one-electron reduction potential. Ellagic acid has also been found to be a good scavenger of peroxynitrite. Using stopped-flow reaction analyzer with absorption detection, the rate constant for this reaction has been determined to be 3.7 x 10(3) M(-1) s (-1). The electron spin resonance spectra of the oxidized ellagic acid radicals have been recorded by horseradish peroxidase and hydrogen peroxide method.
Ellagic acid production and phenolic antioxidant activity in cranberry pomace (Vaccinium macrocarpon) mediated by Lentinus edodes using a solid-state system

Cranberry pomace is a byproduct of the cranberry processing industry that can be targeted for production of value-added phenolic ingredients. Bio-processing of pomace by a solid-state process using food grade fungi provides a unique strategy to improve nutraceutical properties and to produce functional phenolic ingredients. The investigation was carried out to understand the changes and mobilizations of simple phenolics and diphenyl’s and their antioxidant properties in cranberry pomace processed by solid-state growth using food grade fungus Lentinus edodes. The role of β-glucosidase in the mobilization of phenolic antioxidants by hydrolysis of the glycosides was also investigated. During the course of solid-state growth there was an increase in the extractable phenolic content. Antioxidant activity measured by both 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) inhibition system and β-carotene oxidation model system increased over the course of growth. Both phenolics and antioxidant capacity correlated with the increase in the β-glucosidase activity and peaked in a similar manner, showing that the enzyme may play an important role in the release of phenolic aglycones from cranberry pomace and, therefore, increase the antioxidant capacity. In addition, HPLC analysis indicated that the cranberry pomace was enriched with ellagic acid to a level of 350 μg/g dw of pomace.












 

Abacus education, often referred to as abacus math or mental abacus, involves the use of an abacus as a tool to teach mathematical concepts and improve mental math skills. This form of education is particularly popular among young children and is believed to enhance their cognitive abilities and mathematical proficiency. Here are some key aspects of abacus education:

Basic Arithmetic Skills: The abacus is used to teach basic arithmetic operations, including addition, subtraction, multiplication, and division. By physically moving beads on the abacus, students develop a concrete understanding of mathematical concepts.

Visual and Tactile Learning: Abacus education employs a visual and tactile approach to learning. Students manipulate the beads on the abacus, which helps reinforce the understanding of numbers and their relationships. This hands-on experience can enhance comprehension, especially for those who benefit from kinesthetic learning.

Mental Math: One of the primary goals of abacus education is to develop strong mental math skills. As students become proficient with the abacus, they are encouraged to perform calculations mentally, visualizing the movements of the beads without the physical aid of the abacus.

Speed and Accuracy: Abacus training aims to improve both speed and accuracy in mathematical calculations. The repetitive nature of using the abacus helps students become quicker and more precise in their mental calculations over time.

Concentration and Focus: Abacus education requires concentration and focus as students work on solving problems mentally. This can contribute to the development of cognitive skills and attention span.

Cultural and Historical Understanding: Learning to use the abacus also provides students with insights into the cultural and historical aspects of mathematics. Different cultures have their own variations of the abacus, such as the Chinese suanpan or the Japanese soroban.

Supplement to School Curriculum: Abacus education is often used as a supplement to the regular school curriculum. It is considered a complementary method to traditional teaching, offering a unique approach to learning mathematics.

Abacus education programs and courses are available in various educational institutions and online platforms. These programs are typically designed to accommodate different age groups and skill levels. While the abacus itself may not be widely used in everyday life today, the skills developed through abacus education can contribute to overall mathematical proficiency and problem-solving abilities. 
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